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In addition to their insulinotropic effects, GIP and GLP-1 play critical roles in various biological processes in different tissues and organs that express their receptors, including the pancreas, adipose tissue, bone, and the brain
PCOS is strongly associated with insulin resistance and obesity, both of which can impair ovulation
Ibuprofen, being a non-selective NSAID, inhibits both COX-1 and COX-2 enzymes
Ultrathin sections (80 nm thick) were cut with an ultramicrotome (Leica, EMUC6, Germany), and then stained with uranyl acetate and lead citrate and finally examined by a Tecnai G 2 Spirit TWIN transmission electron microscope (FEI, Hillsboro, OR, USA)
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