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For optimal effects, it is important to continue to exercise and follow a healthy, low calorie diet

Redox Rep 5:1467 Fulle S, Mecocci P, Fan G, Vecchiet I, Vecchini A, Racciotti D, Cherubini A, Pizzigallo E, Vecchiet L, Senin U, Beal MF (2000) Specific oxidative alterations in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome

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Nooms clinical review provides a detailed breakdown of the trial data