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Candidates often include individuals with a body mass index (BMI) of 30 or higher, or 27 or higher with weight-related health concerns

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Glucagon receptor activation is thought to increase energy expenditure and promote hepatic fat oxidation, potentially contributing to the substantial weight loss observed in early trials

annual kidney function assessment (serum creatinine, estimated glomerular filtration rate, urine albumin-to-creatinine ratio)more frequent if you have existing kidney disease