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Insulin resistance, oxidative stress, and inflammatory cytokines all increase DPP-4 gene transcription

American Society of Anesthesiologists ASA et al

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Risks of Insulin Tapering In Patients on High-Dose Insulin Adding another antidiabetic medication to patients on high-dose insulinincluding those using multiple daily injections, continuous subcutaneous insulin infusion, or automated insulin delivery systemsalong with sulfonylureas or meglitinides increases the risk of hypoglycemia [39]