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Studies have reported OCTN2 expression in respiratory epithelial cells and alveolar macrophages, which is especially high in the upper lung region [301], and OCTN2-mediated carnitine uptake plays an important role in maintaining respiratory cilia beating and airway mucociliary clearance function, helping to remove excess mucus and potentially harmful substances from the airway [302]
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Persons affected by major depressive disorder manifested acetyl-l-carnitine deficiency compared to age- and sex-matched healthy individuals in two independent study centres
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