9 Limitations of preclinical evidence Despite the growing body of preclinical evidence supporting the neuroprotective potential of astaxanthin, several important limitations should be acknowledged
During the first few weeks, lighter meals and slower eating are often better tolerated
Finally, safety and selectivity considerations will shape the translational path
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Patients with higher insulin resistance or metabolic syndrome may see faster initial fat loss, while those with lower baseline body weight or high metabolic efficiency may progress more gradually
This inactive roGFP2 construct was expressed in HeLa cells and subjected to the same 48-hour timelapse imaging ( Figure 3b )