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The subcutaneous route may be unreliable in patient with conditions that result in impaired blood flow, such as circulatory shock (Dougherty and Lister, 2015)

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Side Effects & Safety GI side effects (nausea, vomiting, diarrhea) are common, particularly during dose escalation, consistent with GLP-1 agonist class effects

GLP-1 agonists are not universally appropriate, and their use requires careful considerationparticularly in individuals with complex medical histories or concurrent medications