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Eur J Endocrinol 191(6):G1G17 Mansur SA, Mieczkowska A, Bouvard B, Flatt PR, Chappard D, Irwin N, Mabilleau G (2015) Stable incretin mimetics counter rapid deterioration of bone quality in type 1 diabetes mellitus
(2023) 16:eadd7220
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Thus, some immunomodulatory drugs such as COX inhibitors exert not only anti-inflammatory outcomes but also antidepressant effects [334]
Both medications work by stimulating GLP-1 receptors in the brain, slowing digestion and increasing fullness, which naturally lowers calorie intake and supports consistent, gradual fat loss over time
GLP-1 also signals appetite centers in the brain, indicating a sense of fullness during and between meals by slowing gastric emptying
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