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The viral genomic ORF8 protein could interact with the 1-chain of Hb, capture the porphyrin and inhibit heme metabolism in the body 149

Proc Natl Acad Sci USA 82:64926496

2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults

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Figure 3 shows a schematic diagram of HisLink Resin and polyhistidine tag interaction

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