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Certain types of drugs can increase the risk of hypoglycemia (low blood sugar) or worsen hypoglycemia when taken with glipizide

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and Robyn Jordan, MD, PhD, associate professor in the Department of Psychiatry and medical director of the UNC Addiction Medicine Program

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For instance, the acylation reaction using L-carnitine and propionyl chloride can be carried out under conditions using dry propionic acid as the solvent and p-toluenesulfonic acid as the catalyst