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Histidine is the direct precursor of histamine and is also an important source of carbon in purine synthesis

In this regard, it is tempting to speculate that the accumulation of succinate (the CII substrate in the TCA cycle) in GSH-deficient FoB (Fig

Ultimately, these advancements contribute significantly to reducing the incidence of high-altitude illnesses and associated complications, ensuring the safety and health of individuals operating in challenging high-altitude environments