pharmacological inhibition of HSP90 (such as geldanamycin) and/or genetic perturbation of HSP90-calcineurin signaling increase the efficacy of azoles and echinocandins against biofilms and reduce the survival of persisters in experimental studies (Robbins et al., 2011)
Dihexa solutions were prepared by suspending dry stock dihexa in DMSO at 3 rag/niL and subsequent serial dilutions in 50% DMSO or HPLC grade water for the final the proteins present in the plasma samples were precipitated using three volumes of ice-cold acetonitrile
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