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BOTTOM LINE: Those at greatest risk of vitamin B12 deficiency are vegans and vegetarians, who get little to no B12 from the diet

Moving forward, a precision medicine framework that integrates genomic, metabolic, and microbiome data will be essential for establishing comprehensive, stratified intervention models and achieving personalized management of MASLDfrom risk prediction to mechanism-based therapy

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Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: a review

In animal models, GLP-1R agonists prevent capillary rarefaction and microvascular barrier dysfunction and reduce apoptosis and reactive oxygen species in microvascular endothelial cells, contributing to improved organ function and reduced progression of microvascular complications [162]