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Brain atrophy is the most direct biological readout of neurodegeneration available short of autopsy

The ADH5 gene is ubiquitously expressed and the encoded protein functions in the oxidation of long-chain primary alcohols and as a formaldehyde dehydrogenase

Tumor necrosis factor activates a conserved innate antiviral response to hepatitis B virus that destabilizes nucleocapsids and reduces nuclear viral DNA

Teduglutide in three different doses, 0.05, 0.1, and 0.2 mg/kg daily, has been investigated in a prospective placebo-controlled study in 100 human subjects for the treatment of moderate to severe CD in an 8-week trial

What if they cause unwanted side effects

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