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Soriano G, Romn E, Crdoba J, et al

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RNA sequencing analysis RNA (1 g) per sample was used for sequencing libraries generation by using KAPA mRNA HyperPrep Kit (KAPA Biosystems, Roche, Basel, Switzerland) following the manufacturers recommendations to remove ribosomal RNA

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This protective effect is independent of GSHs classical antioxidant activity and instead relies on its direct interaction with Cu + , which sequesters excess copper and prevents its aberrant binding to lipoylated proteins within the TCA cycle