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In addition, 4-HNE binding to proteins was reported to disturb the phenotype and function of chondrocytes [89]

Clin Chim Acta 2007;383:5764

These findings underscore that ferroptosis as a core mechanism governing cell fate and the key mediator of DON-induced damageis a critical target to prioritize when screening for DON antagonists

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In early 2010s, Tonstad and coworkers investigated the prevalence of thyroid dysfunction in members of the Seventh-day Adventist church, a population largely following plant-based diets