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Studies have shown that IFN- secreted by cytotoxic T lymphocytes around vitiligo lesions can up-regulate the expression of Hsp70, and Hsp70 can also enhance the release of IFN- by cytotoxic T lymphocytes through a positive feedback mechanism (37)

The question of whether these two can be taken together is common because they both target metabolic health but do so through different pathways

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A significant finding is its effect in pathological scarring models, such as keloids, where it promoted apoptosis in resistant fibroblasts and reduced cell proliferation during the G0/G1 phase of the cell cycle

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Vulvar melanosis has also been associated with lichen sclerosus (see Fig