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In practice, if a therapy is considered, success should be defined with measurable endpointssleep quality, function, waist circumference/body composition (when appropriate), and metabolic markersrather than vague claims alone

10.1186/s12916-022-02366-5 51 YuanS.CarterP.VithayathilM.KarS.MasonA

Regardless, the proportional degree by which apoptosis, ferroptosis, pyroptosis, or other processes are responsible for IR-induced cell death remains an intriguing area for future research

However, beneath the surface, another significant factor is at play which is oxidative stress

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doi: 10.1519/JSC.0000000000003354