48 Enhanced glutamatemediated excitatory neurotransmission is thought to contribute to the hypersynchronization of neuronal networks underlying epileptic foci
This is a very important point
De naam komt voort uit het Latijnse woord Carnis (vlees)
Other metabolites in the sPLS-DA model did not exhibit significant associations with specific Long COVID dimensions (Supplemental Figures S2S4)
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Although the actual mechanisms of MTX-induced liver and kidney damage are unknown, one of the hypotheses is the breakdown in cellular antioxidant defences, which increases the production of reactive oxygen species and nitrogen species, inhibits cytosolic NADP-dependent dehydrogenase and NADP malic enzyme, lowers glutathione (GSH), superoxide dismutase (SOD) and catalase levels and reduces the effectiveness of the antioxidant defence system protecting the cell against reactive oxygen species (Reference Savran, Cicek and Doguc7)