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By following these best practices, patients can receive correct dosing, minimize discomfort, and avoid complications

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This pharmacokinetic profile enables weekly dosing while maintaining stable therapeutic levels throughout the dosing interval

Since nitrous oxide is commonly used for surgery in the elderly, some experts feel vitamin B 12 deficiency should be ruled out prior to its use or prophylactic vitamin B 12 supplementation implemented before and after exposure to the gas (7, 18)

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