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Zimmermann DJ, Voss S, von Unruh GE, Hesse A

Metallothionein suppresses angiotensin II-Induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart

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In addition, the model also tests the possibility of a direct conversion of SetCys amide 5 into final product 6 , being fully aware that the cleavage of the selenoethyl appendage from compound 5 through an ionic mechanism is unlikely due to the poor leaving group ability of imido nitrogens