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Tesamorelin + Ipamorelin Side Effects & Safety Compound-level safety From tesamorelin trials, the most commonly reported adverse events include injection-site reactions (redness, itching), joint pain (arthralgia), pain in the extremities, peripheral edema (fluid retention), and muscle aches

An insightful study by Tolosano et al

Schumer has been candid about her health journey through the years, sharing in December 2025 that she lost 50 pounds as a way to "survive" her battle with Cushing syndrome