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While not yet tested in large human trials, these findings suggest Dihexa may have future therapeutic roles in: Some studies point to Dihexas ability to activate the c-Met receptor , a pathway involved in tissue repair, angiogenesis (formation of new blood vessels), and inflammation modulation

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Together, these observations further support that DMF mediates gene locus-specific regulatory mechanism in an NRF2, DNA hydroxymethylation dependent or both to produce protective effect against ferroptosis in SCD

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