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Considering the severe health consequences and increasing prevalence of obesity, it should come as no surprise that the treatment of obesity attracts considerable research interest

The comparative data presented in Figure 8 (Supplementary Figure S3) suggest that SR18 can predominantly sustain a helical conformation in solution, similar to GLP-1 and Semaglutide, with some noticeable end fraying, specifically in the C-terminus region, which is generally observed for short peptides

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