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Higher doses (90 mg and 120 mg) achieved up to 12.2% mean reduction from baseline (26.6 lbs) versus 1.3% (2.9 lbs) for placebo, with up to 97% of patients losing 5% of body weight
While not currently being studied for weight loss specifically, HU6 activates mitochondrial uncoupling and leads to fat-specific weight loss, preservation of muscle mass, reduction of liver and visceral fat, improved glycemic control and reductions in oxidative stress and inflammation, according to the companys website
However, this anorexigenic action of GLP-1 is maintained through a complex neural circuitry and involves multiple brain areas [25, 31]
Most importantly, it provides advice and tools to aid clinicians in selecting suitable alternatives to GLP-1 RAs where there is limited availability
Plus, it was easy to find help: A company called WhiteLabelMD handles customer service, provides software, and connects patients with clinicians who prescribe drugs like semaglutide and tirzepatide
Over time, theyve gained popularity for their impressive results in weight loss especially in individuals who struggle with stress-related obesity
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