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Older adults maintain the same 1.5 mcg RNI, but absorption efficiency often declines with age due to reduced stomach acid production and intrinsic factor availability

PKA-dependent phosphorylation of perilipin A may facilitate interaction with HSL on the lipid droplet, thereby increasing activity of the enzyme (84)

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Source: (1) Tirzepatide Once Weekly for the Treatment of Obesity, The New England Journal of Medicine homepage [accessed 30 December 2024] (2) MHRA authorises diabetes drug Mounjaro (tirzepatide) for weight management and weight loss, GOVUK [accessed 30 December 2024]

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