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These cohorts serve as compelling examples of the lack of direct GH counter-regulatory effects on pancreatic -cell insulin secretion, thus implying that circulating insulin exerts its glucose-lowering effects more efficiently in these subjects compared with healthy controls

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GLP-1 medications, such as Ozempic and Wegovy, have revolutionized weight loss for many, but their impact on facial appearance often referred to as Ozempic Face has raised growing concerns about rapid facial aging following significant weight loss

doi: 10.1128/msystems.00443-21 196 WalkerC.MortensenM.PoudelB.CotterC.MyersR.OkekeogbuI

PMID: 29141968