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Figure 1 Intriguingly, several key pathological features of PD align remarkably with the triggers and hallmarks of ferroptosis, including amplified lipid peroxidation, increased iron accumulation, suppressed expression of the cysteine-glutamate antiporter (system Xc - ) and diminished glutathione (GSH) levels ( SNCA triplication neurons is approximately 1.5-fold higher than that in control neurons, and exposure to 10 nM -syn oligomers further elevates lipid peroxidation levels ( Consequently, exploring ferroptosis as a pivotal mechanism in dopaminergic neuron demise offers promising avenues for novel therapeutic interventions in PD

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[16] Overall, we find that the measured redox potentials in these compartments were in good agreement with published data, confirming the reliability and versatility of the redesigned sensors

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PRECAUTIONS People with renal inadequacy or other serious disease used with caution