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Furness et al., 2011)

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Distinction : Unlike injectable GLP-1 drugs (like semaglutide/Wegovy), orforglipron is taken orally , which could make it more accessible and appealing to patients

Mildly Elevated Heart Rate (Tachycardia): Some users may notice an increase in heart rate while using these medications

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In parallel, redox-sensitive transcription factors such as NF-B are activated, upregulating adhesion molecules, chemokines, and pro-inflammatory cytokines (7)