Because semaglutide works like a key fitting into a lock (your bodys receptors), a bent or broken molecule wont fit
Weight loss wasnt a priority although she was intrigued that the drug might also help her slim down
clinical evidence shows that optimal dosing depends on individual metabolic markers, baseline metabolic rate, and genetic variants in GLP-1 receptor signaling pathways
56 Long-term overeating and a high-fat, Western-type diet have been shown in many studies to raise the risk of insulin resistance and obesity (particularly in the abdomen), as well as high cholesterol and triglyceride levels and high blood pressure
Nov 2017;27(11):3021-3030
Individual tolerance to either medication varies widely, and combining them elevates the potential for dose-limiting adverse events that may actually reduce treatment adherence