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Dosing as it appears in the literature The Phase 2 protocol used weekly subcutaneous arms of 1, 4, 8 and 12 mg, reached by slow titration from a low starting dose to limit gastrointestinal effects

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There are many factors that influence the cost of medications , including research, manufacturing, marketing, and development costs

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The clinical literature categorizes these into different types based on mechanism and timing

Comparative studies on the safety and efficacy of orlistat against other weight-loss drugs suggest that the side effects linked to orlistat are generally minor and temporary [42]