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GLP-1s provide guardrails for patients by reducing their desire, lowering their threshold for nausea, forcing them to drink at a slower pace and exacerbating the hangover, thereby creating a negative feedback loop in which the patient can continue to drink but simply doesnt do so excessively, le Roux said

Proper patient selection, dose titration, and monitoring can help mitigate many side effects

Another study showed that 7 days of L-citrulline supplementation at a daily dose of 2.4 g significantly improved cycling time trial performance [14]

Ibutamoren is a small molecule rather than a peptide, although it is associated with the same broad receptor pathway

Morgan TM, House JA, Cresci S, Jones P, Allayee H, Hazen SL, Patel Y, Patel RS, Eapen DJ, Waddy SP, Quyyumi AA, Kleber ME, Mrz W, Winkelmann BR, Boehm BO, Krumholz HM , Spertus JA