The water-soluble nature of B12 means several things for patients : the vitamin requires regular dietary intake to maintain optimal levels, it can be lost during food preparation (particularly with prolonged cooking or boiling), and therapeutic doses are generally considered safe as excess is eliminated through the kidneys, though the body's substantial hepatic storage also plays a role in B12 metabolism
10.1016/j.neuropharm.2020.108336 44 GuoY.ChenX.GongP.LiZ.WuY.ZhangJ.et al (2023)
2024 [cited 2024 Dec 5];14(3)
According to the product packaging, it is recommended to take 1 capsule half an hour before breakfast or 1 hour after breakfast
After reconstitution, refrigerate at 28 C, avoid repeated freezethaw cycles, and use within laboratory defined timeframes
Many patients prescribed Ozempic or similar GLP-1 receptor agonist drugs to treat diabetes or support weight management have reported severe and prolonged vomiting, stomach paralysis, intestinal obstruction, and other serious gastrointestinal injuries
