10.3389/fphar.2022.929262 Summary Keywords trimethylamine N-oxide, gut microbiota, chronic diseases, traditional Chinese medicine, inflammation, oxidative stress, metabolic disorders Citation Qin Z, Wu W, Yang X, Wang X, Ding A, Huang Y, Tang J, Jiang S, Zhang P, Qian C, Zhang X, Zhou S, Wang Y, Song Z, Sun M, Wang M, Shen S and Zhu B (2025) The role of trimethylamine N-oxide in disease pathogenesis and the therapeutic potential of traditional Chinese medicine
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Chrysomycin a attenuates neuroinflammation by down-regulating NLRP3/Cleaved Caspase-1 Signaling Pathway in LPS-Stimulated Mice and BV2 cells
Recent multi-omics analyses by Cappellani et al., for instance, have provided strong genetic and proteomic evidence linking DR pathogenesis directly to the activation of specific immune pathways, including the complement system and adaptive T-cell responses [53, 58, 59]