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This metabolic shift increases relative dehydration riska critical concern because creatine supplementation draws intracellular water, further stressing hydration status

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Funding This work was supported by a Steno Collaborative Grant, Novo Nordisk Foundation, Denmark (Grant no

For medicines that must be maintained at 2C to 8C: Use a validated cool box or insulated travel case with a temperature monitor to maintain the cold chain Use ice packs or gel packs, but ensure they do not come into direct contact with the pen or vial, as localised freezing can damage the product Monitor the temperature throughout the journey where possible For medicines where the label permits storage at up to 25C or 30C for a defined period, an evaporative cooling wallet may be appropriate but only if the product label explicitly allows storage at those temperatures

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Targeting the CD47-SIRP innate immune checkpoint to potentiate antibody therapy in cancer by neutrophils