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For severe B12 deficiency that maybe causing significant neurological symptoms, your doctor may use injectable form of B12 initially before transitioning to oral therapy

We recommend opting for methylcobalamin-based supplements like our B12 Spray (featuring 500mcg) or methylcobalamin+adenosylcobalamin options like our Essential Multivitamin For Vegans (400 mcg) which with the combined vitamins boosts bioavailability and makes the most out of B12's incredibly energizing properties

Most longevity-orientated protocols stack them

The one you get can affect both the price and how often youll need a top-up

Frequency of Use More frequent withdrawals increase contamination risk

Medical Review REGEN scientific content was reviewed for accuracy on 2026-07-19 By Dr