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NICE guidance (NG28) recommends considering GLP-1 receptor agonists for adults with type 2 diabetes when glycaemic targets are not achieved with other therapies, particularly in those with established cardiovascular disease or at high cardiovascular risk

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these reductions are similar to those of other glucose-lowering agents [28]

FIGURE 4 3 Application of ferroptosis inhibitors in diabetes-associated cognitive dysfunction Although inhibitors of ferroptosis demonstrate efficacy in ameliorating DACD, no specific therapeutic agent has yet received clinical approval for this indication