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B12 injections should definitely not be avoided if you have pernicious anemea and can not absorb b12 through the gut due to low stomach acid ,

Persistent effects beyond two weeks suggest considering dose reduction

doi:10.1016/j.bjorl.2015.04.016

Many patients begin to notice improvements in energy and body composition within a few weeks of starting therapy

Wegovy pens last for 6 weeks out of the fridge, however, they only contain enough medication for 4 weeks worth of injections, so you should not need to dispose of any pens unless you miss several doses

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