JeanGilles explains that modest changes in hunger or appetite are expected early on, and side effects like mild fatigue or stomach upset tend to lessen as treatment continues
She said theyre statistically at higher risk of developing conditions such as Type 2 diabetes and heart and liver disease
Weight reduction results in decreased neuroinflammation, which likely translates into improved outcomes of psychiatric co-morbidities
GLP-1 for weight loss Medically reviewed by Dr Crystal Wyllie Last reviewed: 19 Jun 2026 Glucagon-like peptide-1 (GLP-1) agonists are a popular weight loss treatment in the UK
Tirzepatide tends to be the better fit when: the goal is more significant weight loss (15 percent or more of body weight), the patient has type 2 diabetes with A1C above target on prior therapies, prior single-pathway GLP-1 use produced limited results, or the patient tolerated GLP-1s reasonably well and wants a stronger next step
4,6 kg), przy czym efekt zaley od populacji, dawki i czasu terapii