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Senescence is a state in which a cell permanently exits the cellcycle (no longer divides) in response to stress such as DNA damage, telomere shortening, oncogene activation, oxidative stress, or replicative exhaustion

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Together, they address hydration, energy production, immune function, and cellular recovery within a single infusion

This insulin resistance further induces vasoactive substances that cause microvascular insufficiency and local tissue hypoxia with progressive miniaturization of hair follicles

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