However, SGLT2 inhibitors in combination with a GLP1-RA significantly reduced HbA1c in obese subjects without diabetes, compared to placebo (Table 1) [30, 31]
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Since muscle loss has such a detrimental impact on a patient's prognosis and quality of life, developing effective treatment options to combat muscle wasting is a crucial goal of research (Furrer and Handschin, 2019, Sawicka et al., 2018)
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Table 2 Signal detection for GLP-1 RAs-associated gastrointestinal adverse events