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With a family history in textile manufacturing, he himself studied design in Milan (which explained his fluent Italian everywhere we went together)

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Although the shown enhancement of POMC neuronal activity is likely to contribute to the observed increased weight loss with GLP-1GIPLani relative to GLP-1GIP, mechanisms in the hindbrain are also known to account for GLP-1-induced weight loss, and may thus also have a role in the increased weight loss induced by GLP-1GIPLani relative to GLP-1GIP

Moreover, neuropeptides like orexins regulate sleep-wake cycles and interact with monoaminergic pathways, further implicating their role in depression pathophysiology [83, 84]

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