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These data suggest that plants and some microbial TyrA orthologs share an evolutionarily conserved substrate specificity mechanism, and that acquisition of the key active site acidic residue was crucial in evolution of arogenate-specific TyrA a enzymes in plants and closely-related microbes

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Specifications Sources & References Peer-reviewed research Current Pharmaceutical Design Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract 2010 DOI: 10.2174/138161210791164162 PMID: 20388119 Sikiric P, Seiwerth S, Rucman R, et al

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All participants will receive initial weekly subcutaneous doses of VK2735 or placebo for an induction period, after which participants are transitioned to a range of VK2735 maintenance dosing regimens including weekly, every other week, and monthly dosing, or placebo