In a 72-week study, participants receiving the maximum dose of tirzepatide lost an average of 21% of their body weight, while the placebo group experienced a 3% loss
doi: 10.1016/j.pneurobio.2005.06.004 78 MrakREGriffinWST

Ingredients: Water, Ethylhexyl Methoxycinnamate, Butylene Glycol, Ethylhexyl Salicylate, Octocrylene, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Butyl Methoxydibenzoylmethane, Dipropylene Glycol, Niacinamide (20,000ppm), Squalane, C14-22 Alcohols, 1,2-Hexanediol, Polyglyceryl-2 Stearate, Propanediol, Hydroxyacetophenone, Glyceryl Stearate, Stearyl Alcohol, C12-20 Alkyl Glucoside, Tromethamine, Centella Asiatica Extract (1,510ppm), Carbomer, Melaleuca Alternifolia (Tea Tree) Extract, Hippophae Rhamnoides Fruit Extract, Vitis Vinifera (Grape) Fruit Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Uncaria Sinensis Extract, Glycerin, Adenosine, Disodium EDTA, Oryza Sativa (Rice) Bran Extract, Hydrogenated Phosphatidylcholine, Caprylic/Capric Triglyceride, Sodium Hyaluronate, Glucose, Hydrolyzed Collagen, Sucrose Stearate, Glutathione (10ppm), Cyclodextrin, Cetearyl Alcohol, Caprylyl Glycol, Beta-Glucan, Caprylhydroxamic Acid, Ethylhexylglycerin, Asiatic Acid, Asiaticoside, Madecassic Acid, Madecassoside, Tropolone, Hyaluronic Acid, Potassium Hyaluronate

Skin reactions with transdermal-DMSO use Users applying Dihexa transdermally in DMSO describe local skin reactions redness, itching, irritation, or a burning sensation at the application site
10.1007/s00018-020-03715-4 23
Talk with your prescribing physician and ask about other transdermal options, including gel packets, gel pumps, and sprays, says Cole