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To consider whether gut microbiota abundance can be used as a biomarker for patients with CKD

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Exploring non-pharmacological interventions, such as dietary modifications, functional foods, and lifestyle changes, in managing oxidative stress is an important area of research

Important safety considerations include: Inform your GP about all supplements you are taking Avoid self-treating suspected deficiency without medical assessment, as supplementation can mask underlying pernicious anaemia whilst allowing neurological damage to progress Do not start high-dose folic acid supplements before B12 deficiency is excluded, as this can worsen neurological damage Check for interactions if taking medications such as metformin, chloramphenicol, or proton pump inhibitors Monitor response through appropriate blood tests if treating deficiency Pregnant women, individuals with Leber's disease (a rare hereditary eye condition), and those with cobalt allergy should consult healthcare professionals before supplementing

doi: 10.1519/1533-4287(2003)0172.0.co;2

M., Kber, L