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This is because of the connection between weight and the hypothalamic-pituitary-ovarian axis, according to a 2020 article in The Journal of Clinical Endocrinology and Metabolism

Pivari F, Mingione A, Piazzini G, Ceccarani C, Ottaviano E, Brasacchio C, et al

Personalized care: Some providers use microdosing for individuals who prefer more incremental steps or who are sensitive to changes in appetite or digestion