However, long-term human safety trials are lacking, so usage should be approached with caution
Research has demonstrated that GHK-Cu treatment increases production of collagen (particularly type I and type III collagen, the predominant structural collagens in skin and connective tissues), glycosaminoglycans (including hyaluronic acid, which provides hydration, volume, and biochemical signaling in skin), decorin (a small proteoglycan involved in collagen fibril organization and growth factor regulation), and other matrix molecules critical for tissue structure and function
however, scientific research has struggled to demonstrate tangible evidence of these theoretical effects
Fromm, 2012
Improved client-side prediction to reduce "ghost shots"
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