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Interestingly, functional and structural plasticity of excitatory synapses share a complete set of molecular machinery that allows coordinated changes in synaptic strength and architecture (Lscher et al., 2000)

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For in vivo experiments, the alpha-adrenergic blocker phentolamine, the beta-adrenergic blocker propranolol, the HCN channel blocker ivabradine, and the ganglion blocker hexamethonium were purchased from Sigma-Aldrich