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10.1016/j.etap.2016.10.017 [DOI] [PubMed] [Google Scholar] 21.Bota AB, Simmons JG, DiBattista A, Wilson K

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No severe TEAEs or serious TEAEs were observed in either study

Newly exposed hydrophobic transmembrane domains of membrane substrates are prone to aggregation in the cytoplasm, which is prevented by BCL-2-associated athanogene 6 (BAG6)