Timestamps 00:00 Cold open: 200 years of menopause medicine 03:23 Welcome and roadmap 04:20 The HPG axis, follicles, and the FSH lag 09:11 STRAW+10 staging and the timing of perimenopause 13:47 Austin: the 49-year-old with a hormone panel 20:00 Loraine: the OB-GYN workup 28:00 Symptom attribution: what menopause actually causes 33:46 Austin: the all-estrogen patient 37:58 VMS duration and the KNDy mechanism (Avis, SKYLIGHT) 43:53 Austin: who actually gets fezolinetant 47:22 The WHI 24-year correction (Manson, Chlebowski, Boardman) 01:00:15 Modern prescribing today 01:06:52 Where the menopause-content space gets it right and wrong 01:11:50 Testosterone, compounded bioidenticals, and DUTCH panels 01:24:13 Takeaways What we cover The HPG axis and the estrogen shield: what is happening across the 35-year reproductive era and what changes at perimenopause
Diabetes Care 33 , 15911597 (2010)
14 Research has shown that omega-3 fatty acids modulate inflammatory processes by altering the phospholipid composition of cell membranes
Stimulation of the cyclooxygenase enzyme is brought about by ROS via activation of the transcription factor NFKappa , suggesting a mechanism for menstruation [83]
2022 Prebiotics and probiotics for autism spectrum disorder: a systematic review and meta-analysis of controlled clinical trials
You know, like, how far do you have to go back in human history